Anti-Human Fc gamma RIIIA/CD160 Reference Antibody (ELB021, RUO) (HF985026)

Name: Anti-Human Fc gamma RIIIA/CD160 Reference Antibody (ELB021, RUO)
Brand: abinScience
SKU: HF985026
Price: 370 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HF985026

Species reactivity

Human

Applications

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

Host species

Human

Isotype

IgG

Clone ID

ELB021

Expression system

Mammalian cells

Clonality

Monoclonal

Target

Natural killer cell receptor BY55, CD160 antigen, CD160, BY55

Endotoxin level

Please contact the lab for this information.

Purity

>95% purity as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O95971

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternate Names

ELB021

Background

CD160 antigen is a ~19 kDa protein. Receptor on immune cells capable to deliver stimulatory or inhibitory signals that regulate cell activation and differentiation. Exists as a GPI-anchored and as a transmembrane form, each likely initiating distinct signaling pathways via phosphoinositol 3-kinase in activated NK cells and via LCK and CD247/CD3 zeta chain in activated T cells. Receptor for both classical and non-classical MHC class I molecules. In the context of acute viral infection, recognizes HLA-C and triggers NK cell cytotoxic activity, likely playing a role in anti-viral innate immune response. On CD8+ T cells, binds HLA-A2-B2M in complex with a viral peptide and provides a costimulatory signal to activated/memory T cells.

1. Nikolova, M. et al. (2002) International immunology 14, 445-51. PMID: 11978774

2. Rabot, M. et al. (2007) International immunology 19, 401-9. PMID: 17307798

3. Giustiniani, J. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 182, 63-71. PMID: 19109136

4. Le Bouteiller, P. et al. (2002) Proceedings of the National Academy of Sciences of the United States of America 99, 16963-8. PMID: 12486241

5. Agrawal, S. et al. (1999) Journal of immunology (Baltimore, Md. : 1950) 162, 1223-6. PMID: 9973372

6. Viganò, S. et al. (2014) PLoS pathogens 10, e1004380. PMID: 25255144

7. Fons, P. et al. (2006) Blood 108, 2608-15. PMID: 16809620

8. Cai, G. et al. (2008) Nature immunology 9, 176-85. PMID: 18193050

References

1. Henderson LJ, et al. Advances toward Curing HIV-1 Infection in Tissue Reservoirs. J Virol. 2020;94(3):e00375-19. Published 2020 Jan 17. [HF985026]

Note

For research use only. Not suitable for clinical or therapeutic use.

Images

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CD160 (ELB021)

References

Datasheet

Anti-Human Fc gamma RIIIA/CD160 Reference Antibody (ELB021, RUO).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human Fc gamma RIIIA/CD160 Reference Antibody (ELB021, RUO) (HF985026)

Overview

Images

References

Datasheet

SDS

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