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Anti-Human Cathepsin S Reference Antibody (Fsn0503h, RUO) (HB729016)

Anti-Human Cathepsin S Reference Antibody (Fsn0503h, RUO)
Anti-Human Cathepsin S Reference Antibody (Fsn0503h, RUO)
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Especificación:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
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Vista general
Número de catálogoHB729016
Descripción
Anti-Human CTSS/Cathepsin S Antibody (Fsn0503h) (HB729016) is a research-grade recombinant antibody targeting CTSS. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especiesHuman
AplicacionesELISA, Bioactivity: FCM, Functional assay, Research in vivo
Especie huéspedHuman
ClonalidadMonoclonal
IsotipoIgG
ID de clonFsn0503h
Sistema de expresión Mammalian cells
Objetivo CTSS, Cathepsin S
Nivel de endotoxinas < 10 EU/mg
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P25774
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Cathepsin S (CTSS) is a ~37 kDa protein. Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L. Elicits itch by mediating cleavage and activation of MRGPRX1.

1. Baranov, MV. et al. (2019) iScience 11, 160-177. PMID: 30612035
Nota For research use only. Not suitable for clinical or therapeutic use.
Imágenes
  • Anti-Human Cathepsin S Reference Antibody (Fsn0503h, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human CTSS/Cathepsin S Antibody (Fsn0503h)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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