

| Catalog No. | HB729014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-CTSS Polyclonal Antibody (HB729014) is a rabbit polyclonal antibody detecting CTSS in ELISA, IHC, WB. Suitable for Human and Dog.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human CTSS (Leu115-Ile331). | ||||||||
| Target | CTSS, Cathepsin S | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P25774 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Cathepsin S (CTSS) is a ~37 kDa protein. Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L. Elicits itch by mediating cleavage and activation of MRGPRX1. 1. Baranov, MV. et al. (2019) iScience 11, 160-177. PMID: 30612035 | ||||||||
| Note | For research use only. |




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