

| Catalog No. | HB729016 |
|---|---|
| Description |
Anti-Human CTSS/Cathepsin S Antibody (Fsn0503h) (HB729016) is a research-grade recombinant antibody targeting CTSS. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| Species reactivity | Human |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Host species | Human |
| Isotype | IgG |
| Clone ID | Fsn0503h |
| Expression system | Mammalian cells |
| Target | CTSS, Cathepsin S |
| Endotoxin level | < 10 EU/mg |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P25774 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Background | Cathepsin S (CTSS) is a ~37 kDa protein. Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L. Elicits itch by mediating cleavage and activation of MRGPRX1. 1. Baranov, MV. et al. (2019) iScience 11, 160-177. PMID: 30612035 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Anti-Human CTSS/Cathepsin S Antibody (Fsn0503h)




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