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Anti-Human Cathepsin S Reference Antibody (Fsn0503h, RUO) (HB729016)

Anti-Human Cathepsin S Reference Antibody (Fsn0503h, RUO)
Anti-Human Cathepsin S Reference Antibody (Fsn0503h, RUO)
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Aperçu
Numéro de catalogueHB729016
Description
Anti-Human CTSS/Cathepsin S Antibody (Fsn0503h) (HB729016) is a research-grade recombinant antibody targeting CTSS. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesHuman
ApplicationsELISA, Bioactivity: FCM, Functional assay, Research in vivo
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG
ID de cloneFsn0503h
Système d'expression Mammalian cells
Cible CTSS, Cathepsin S
Niveau d'endotoxines < 10 EU/mg
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P25774
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Cathepsin S (CTSS) is a ~37 kDa protein. Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L. Elicits itch by mediating cleavage and activation of MRGPRX1.

1. Baranov, MV. et al. (2019) iScience 11, 160-177. PMID: 30612035
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human Cathepsin S Reference Antibody (Fsn0503h, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human CTSS/Cathepsin S Antibody (Fsn0503h)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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