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| カタログ番号 | HB729016 |
|---|---|
| 説明 |
Anti-Human CTSS/Cathepsin S Antibody (Fsn0503h) (HB729016) is a research-grade recombinant antibody targeting CTSS. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 種反応性 | Human |
| アプリケーション | ELISA, Bioactivity: FCM, Functional assay, Research in vivo |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG |
| クローンID | Fsn0503h |
| 発現システム | Mammalian cells |
| ターゲット | CTSS, Cathepsin S |
| エンドトキシンレベル | < 10 EU/mg |
| 純度 | >95% as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | P25774 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Cathepsin S (CTSS) is a ~37 kDa protein. Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L. Elicits itch by mediating cleavage and activation of MRGPRX1. 1. Baranov, MV. et al. (2019) iScience 11, 160-177. PMID: 30612035 |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Anti-Human CTSS/Cathepsin S Antibody (Fsn0503h)
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中国武漢市深敦寺路666号C棟、武漢、430206
