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Anti-Human Growth Hormone R/GHR Reference Antibody (DR10112, RUO) (HY420016)

Anti-Human Growth Hormone R/GHR Reference Antibody (DR10112, RUO)
Anti-Human Growth Hormone R/GHR Reference Antibody (DR10112, RUO)
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Aperçu
Numéro de catalogueHY420016
Description
Anti-Human GHR (DR10112) (HY420016) is a research-grade recombinant antibody targeting GHR. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG
ID de cloneDR10112
Système d'expression Mammalian cells
Cible GHR, GH-binding protein, Growth hormone receptor, GHBP, Somatotropin receptor, GH receptor, Serum-binding protein
Niveau d'endotoxines < 10 EU/mg
Pureté >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P10912
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsDR10112
Contexte

Growth hormone receptor (GHR) is a ~71 kDa protein. Receptor for pituitary gland growth hormone (GH1) involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway.

1. de Vos, AM. et al. (1992) Science (New York, N.Y.) 255, 306-12. PMID: 1549776
2. Leung, DW. et al. (1987) Nature 330, 537-43. PMID: 2825030
3. Sundström, M. et al. (1996) The Journal of biological chemistry 271, 32197-203. PMID: 8943276
4. Greenhalgh, CJ. et al. (2005) The Journal of clinical investigation 115, 397-406. PMID: 15690087
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human Growth Hormone R/GHR Reference Antibody (DR10112, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human GHR (DR10112)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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