

| Catalog No. | HY420014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human GHR (Lys315-Thr574). | ||||||||
| Target | GHR, GH-binding protein, Growth hormone receptor, GHBP, Somatotropin receptor, GH receptor, Serum-binding protein | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P10912 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Growth hormone receptor (GHR) is a ~71 kDa protein. Receptor for pituitary gland growth hormone (GH1) involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. 1. de Vos, AM. et al. (1992) Science (New York, N.Y.) 255, 306-12. PMID: 1549776 2. Leung, DW. et al. (1987) Nature 330, 537-43. PMID: 2825030 3. Sundström, M. et al. (1996) The Journal of biological chemistry 271, 32197-203. PMID: 8943276 4. Greenhalgh, CJ. et al. (2005) The Journal of clinical investigation 115, 397-406. PMID: 15690087 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-Human GHR polyclonal antibody at 1ug/mL on recombinant Human GHR (Catalog No. HY420012).



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