Anti-Human Growth Hormone R/GHR Reference Antibody (DR10112, RUO) (HY420016)

Name: Anti-Human Growth Hormone R/GHR Reference Antibody (DR10112, RUO)
Brand: abinScience
SKU: HY420016
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	HY420016
Description	Anti-Human GHR (DR10112) (HY420016) is a research-grade recombinant antibody targeting GHR. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	DR10112
Expression system	Mammalian cells
Clonality	Monoclonal
Target	GHR, GH-binding protein, Growth hormone receptor, GHBP, Somatotropin receptor, GH receptor, Serum-binding protein
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P10912
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	DR10112
Background	Growth hormone receptor (GHR) is a ~71 kDa protein. Receptor for pituitary gland growth hormone (GH1) involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. 1. de Vos, AM. et al. (1992) Science (New York, N.Y.) 255, 306-12. PMID: 1549776 2. Leung, DW. et al. (1987) Nature 330, 537-43. PMID: 2825030 3. Sundström, M. et al. (1996) The Journal of biological chemistry 271, 32197-203. PMID: 8943276 4. Greenhalgh, CJ. et al. (2005) The Journal of clinical investigation 115, 397-406. PMID: 15690087
Note	For research use only. Not suitable for clinical or therapeutic use.