

| Número de catálogo | HV664026 |
|---|---|
| Descripción |
Anti-Human GP6/GPVI Antibody (hu9O12.2) (HV664026) is a research-grade recombinant antibody targeting Platelet glycoprotein VI. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| Reactividad de especies | Human |
| Aplicaciones | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Especie huésped | Human |
| Clonalidad | Monoclonal |
| Isotipo | IgG1, kappa |
| ID de clon | hu9O12.2 |
| Sistema de expresión | Mammalian cells |
| Objetivo | Platelet glycoprotein VI, GP6, GPVI, Glycoprotein 6 |
| Nivel de endotoxinas | < 10 EU/mg |
| Pureza | >95% purity as determined by SDS-PAGE. |
| Purificación | Protein A/G purified from cell culture supernatant. |
| Número de acceso | Q9HCN6 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Nombres alternativos | 9O12, 9O12.2, hscFv9O12.2(1), Humanized9O12.2 |
| Fondo | Platelet glycoprotein VI (GP6/GPVI) is a ~36 kDa protein. Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2. |
| Nota | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |

SDS-PAGE for Research Grade Anti-Human GP6/GPVI Antibody (hu9O12.2)




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