

| Catalog No. | HV664137 |
|---|---|
| Species reactivity | Human |
| Applications | FCM |
| Host species | Human |
| Isotype | IgG1, kappa |
| Clone ID | SAA0163 |
| Conjugation | APC |
| Clonality | Monoclonal |
| Target | Platelet glycoprotein VI, GP6, GPVI, Glycoprotein 6 |
| Endotoxin level | Please contact with the lab for this information. |
| Associated products | Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC |
| Accession | Q9HCN6 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Background | Platelet glycoprotein VI (GP6/GPVI) is a ~36 kDa protein. Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2. |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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