Anti-Human GPVI Reference Antibody (hu9O12.2, RUO) (HV664026)

Name: Anti-Human GPVI Reference Antibody (hu9O12.2, RUO)
Brand: abinScience
SKU: HV664026
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	HV664026
Description	Anti-Human GP6/GPVI Antibody (hu9O12.2) (HV664026) is a research-grade recombinant antibody targeting Platelet glycoprotein VI. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1, kappa
Clone ID	hu9O12.2
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Platelet glycoprotein VI, GP6, GPVI, Glycoprotein 6
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9HCN6
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	9O12, 9O12.2, hscFv9O12.2(1), Humanized9O12.2
Background	Platelet glycoprotein VI (GP6/GPVI) is a ~36 kDa protein. Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Anti-Human GP6/GPVI Antibody (hu9O12.2)

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Datasheet

Anti-Human GPVI Reference Antibody (hu9O12.2, RUO).pdf

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Anti-Human GPVI Reference Antibody (hu9O12.2, RUO) (HV664026)

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