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Anti-Human HLA-DR Reference Antibody (IMMU-140, RUO) (HM826016)

Anti-Human HLA-DR Reference Antibody (IMMU-140, RUO)
Anti-Human HLA-DR Reference Antibody (IMMU-140, RUO)
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Aperçu
Numéro de catalogueHM826016
Description
Anti-Human HLA-DR (IMMU-140) (HM826016) is a research-grade recombinant antibody targeting CD74. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG
ID de cloneIMMU-140
Système d'expression Mammalian cells
Cible HLA-DR antigens-associated invariant chain, HLA class II histocompatibility antigen gamma chain, CD74, CLIP, Ia antigen-associated invariant chain, DHLAG, Ii
Niveau d'endotoxines < 10 EU/mg
Pureté >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P04233
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsIMMU-140, IMMU140, IMMU140
Contexte

HLA class II histocompatibility antigen gamma chain (IMMU-140) is a ~33 kDa protein. Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human HLA-DR Reference Antibody (IMMU-140, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human HLA-DR (IMMU-140)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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