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Anti-Human CD74 Reference Antibody (Stro-001, RUO) (HY465026)

Anti-Human CD74 Reference Antibody (Stro-001, RUO)
Anti-Human CD74 Reference Antibody (Stro-001, RUO)
Anti-Human CD74 Reference Antibody (Stro-001, RUO)
Anti-Human CD74 Reference Antibody (Stro-001, RUO)
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  • Overview

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  • Datasheet

  • SDS

Overview
Catalog No.HY465026
Description
STRO-001 (HY465026) is a research-grade recombinant antibody targeting CD74. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG1-nd
Expression system Mammalian cells
Clonality Monoclonal
Target HLA-DR antigens-associated invariant chain, HLA class II histocompatibility antigen gamma chain, CD74, CLIP, Ia antigen-associated invariant chain, DHLAG, Ii
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P04233
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesSP7219
Background

HLA class II histocompatibility antigen gamma chain (CD74) is a ~33 kDa protein. Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human CD74 Reference Antibody (Stro-001, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade STRO-001.

  • Anti-Human CD74 Reference Antibody (Stro-001, RUO)

    Bioactivity

    Detects recombinant CD74 (Catalog No: HY465011) in indirect ELISA.

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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