

| Numéro de catalogue | HY419016 |
|---|---|
| Description |
Anti-Human Amylin/DAP Reference Antibody (NI-203, RUO) (HY419016) is a human monoclonal antibody detecting IAPP. Expressed in Mammalian cells.
|
| Reactivité des espèces | Human |
| Applications | ELISA, Bioactivity: FCM, Functional assay, Research in vivo |
| Espèce hôte | Human |
| Clonalité | Monoclonal |
| Isotype | IgG |
| ID de clone | NI-203 |
| Système d'expression | Mammalian cells |
| Nature | Recombinant |
| Cible | IAPP, Islet amyloid polypeptide, Diabetes-associated peptide, Insulinoma amyloid peptide, Amylin, DAP |
| Niveau d'endotoxines | < 10 EU/mg as determined by LAL method. |
| Pureté | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Numéro d'accès | P10997 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | NI-203, NI203, NI203 |
| Contexte | Islet amyloid polypeptide (IAPP) is a ~9 kDa protein. Amylin/IAPP is a glucoregulatory peptide hormone that plays an important role in the regulation of energy homeostasis. Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. IAPP function is mediated by the CALCR-RAMPs (AMYRs) receptor complexes. Amylin can also bind CALCR receptor in the absence of RAMPs, although it is more selective for AMYRs. 1. Roberts, AN. et al. (1989) Proceedings of the National Academy of Sciences of the United States of America 86, 9662-6. PMID: 2690069 |
| Reférences | 1. https://synapse.zhihuiya.com/drug/d0641a1ffcf6403e8a491542a778527a [HY419016] |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |

SDS-PAGE for Research Grade Anti-Human IAPP (NI-203)




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