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Anti-Human Amylin/DAP Reference Antibody (NI-203, RUO) (HY419016)

Anti-Human Amylin/DAP Reference Antibody (NI-203, RUO)
Anti-Human Amylin/DAP Reference Antibody (NI-203, RUO)
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Aperçu
Numéro de catalogueHY419016
Description
Anti-Human Amylin/DAP Reference Antibody (NI-203, RUO) (HY419016) is a human monoclonal antibody detecting IAPP. Expressed in Mammalian cells.
Reactivité des espècesHuman
ApplicationsELISA, Bioactivity: FCM, Functional assay, Research in vivo
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG
ID de cloneNI-203
Système d'expression Mammalian cells
Nature Recombinant
Cible IAPP, Islet amyloid polypeptide, Diabetes-associated peptide, Insulinoma amyloid peptide, Amylin, DAP
Niveau d'endotoxines < 10 EU/mg as determined by LAL method.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P10997
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsNI-203, NI203, NI203
Contexte

Islet amyloid polypeptide (IAPP) is a ~9 kDa protein. Amylin/IAPP is a glucoregulatory peptide hormone that plays an important role in the regulation of energy homeostasis. Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. IAPP function is mediated by the CALCR-RAMPs (AMYRs) receptor complexes. Amylin can also bind CALCR receptor in the absence of RAMPs, although it is more selective for AMYRs.

1. Roberts, AN. et al. (1989) Proceedings of the National Academy of Sciences of the United States of America 86, 9662-6. PMID: 2690069
Reférences 1. https://synapse.zhihuiya.com/drug/d0641a1ffcf6403e8a491542a778527a [HY419016]
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)
Images
  • Anti-Human Amylin/DAP Reference Antibody (NI-203, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human IAPP (NI-203)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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