Anti-Human IAPP Polyclonal Antibody (HY419014)

Name: Anti-Human IAPP Polyclonal Antibody
Brand: abinScience
SKU: HY419014
Price: 168 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HY419014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human IAPP (Thr23-Leu89).

Target

IAPP, Islet amyloid polypeptide, Diabetes-associated peptide, Insulinoma amyloid peptide, Amylin, DAP

Purification

Purified by antigen affinity column.

Accession

P10997

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Islet amyloid polypeptide (IAPP) is a ~9 kDa protein. Amylin/IAPP is a glucoregulatory peptide hormone that plays an important role in the regulation of energy homeostasis. Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. IAPP function is mediated by the CALCR-RAMPs (AMYRs) receptor complexes. Amylin can also bind CALCR receptor in the absence of RAMPs, although it is more selective for AMYRs.

1. Roberts, AN. et al. (1989) Proceedings of the National Academy of Sciences of the United States of America 86, 9662-6. PMID: 2690069

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Human IAPP polyclonal antibody at 1ug/mL on recombinant Human IAPP (Catalog No. HY419012).

References

Datasheet