

| Каталожный номер | HY419016 |
|---|---|
| Описание |
Anti-Human Amylin/DAP Reference Antibody (NI-203, RUO) (HY419016) is a human monoclonal antibody detecting IAPP. Expressed in Mammalian cells.
|
| Реактивность видов | Human |
| Применения | ELISA, Bioactivity: FCM, Functional assay, Research in vivo |
| Хозяинский вид | Human |
| Клоональность | Monoclonal |
| Изотип | IgG |
| ID клона | NI-203 |
| Система экспрессии | Mammalian cells |
| Характер | Recombinant |
| Цель | IAPP, Islet amyloid polypeptide, Diabetes-associated peptide, Insulinoma amyloid peptide, Amylin, DAP |
| Уровень эндотоксинов | < 10 EU/mg as determined by LAL method. |
| Чистота | >95% as determined by SDS-PAGE. |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | P10997 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | NI-203, NI203, NI203 |
| Фон | Islet amyloid polypeptide (IAPP) is a ~9 kDa protein. Amylin/IAPP is a glucoregulatory peptide hormone that plays an important role in the regulation of energy homeostasis. Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. IAPP function is mediated by the CALCR-RAMPs (AMYRs) receptor complexes. Amylin can also bind CALCR receptor in the absence of RAMPs, although it is more selective for AMYRs. 1. Roberts, AN. et al. (1989) Proceedings of the National Academy of Sciences of the United States of America 86, 9662-6. PMID: 2690069 |
| Ссылки | 1. https://synapse.zhihuiya.com/drug/d0641a1ffcf6403e8a491542a778527a [HY419016] |
| Примечание | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |

SDS-PAGE for Research Grade Anti-Human IAPP (NI-203)




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