Anti-Human IL-17E/IL-25 Reference Antibody (ABM109, RUO) (HV984016)

Name: Anti-Human IL-17E/IL-25 Reference Antibody (ABM109, RUO)
Brand: abinScience
SKU: HV984016
Price: 176 USD
Availability: InStock

Datasheet Compartir producto Copiar información

Precio(USD):

Especificación:

100ug
1mg
5mg
10mg
25mg
50mg
100mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo	HV984016
Descripción	Anti-Human IL25/IL17E Antibody (ABM109) (HV984016) is a research-grade recombinant antibody targeting Interleukin-25. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1, kappa
ID de clon	ABM109
Sistema de expresión	Mammalian cells
Objetivo	Interleukin-25, IL-25, IL17E, IL25, IL-17E, Interleukin-17E
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q9H293
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo	Interleukin-25 (IL25/IL17E) is a ~20 kDa protein. Cytokine produced by various cells such as eosinophils, T-helper type 2 (Th2) cells or epithelial cells that plays a role in internal safety of adaptive immune responses by regulating cytokine production. Promotes and augments T-helper type 2 responses locally or systemically. Exerts its activity via its receptor composed of IL17RA and IL17RB for signal transduction. In turn, stimulates the JAK2-STAT5A pathway and promotes the secretion of type-2 associated cytokines including IL4, IL9 and IL13. Also induces the release of IL8, and IL6 from eosinophils through the combined activation of MAPK and NF-kappa-B pathways. 1. Wong, CK. et al. (2005) American journal of respiratory cell and molecular biology 33, 186-94. PMID: 15860795 2. Wu, L. et al. (2015) Journal of immunology (Baltimore, Md. : 1950) 194, 4528-34. PMID: 25821217 3. Fort, MM. et al. (2001) Immunity 15, 985-95. PMID: 11754819
Nota	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)