Anti-Human Lymphotoxin beta R/TNFRSF3 Reference Antibody (CBE-11, RUO) (HW495016)

Name: Anti-Human Lymphotoxin beta R/TNFRSF3 Reference Antibody (CBE-11, RUO)
Brand: abinScience
SKU: HW495016
Price: 370 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HW495016
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1-kappa
ID de clone	CBE-11
Système d'expression	Mammalian cells
Cible	Tumor necrosis factor receptor superfamily member 3, Lymphotoxin-beta receptor, Tumor necrosis factor C receptor, Tumor necrosis factor receptor 2-related protein, Tumor necrosis factor receptor type III, TNF-RIII, TNFR-III, LTBR, D12S370, TNFCR, TNFR3, TNFRSF3
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P36941
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	hCBE-11, CBE-11, HCBE11, CBE11, CBE11
Contexte	Tumor necrosis factor receptor superfamily member 3 (LTBR/TNFR-III) is a ~46 kDa protein. Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Activates NF-kappa-B signaling pathway upon stimulation with lymphotoxin (LTA(1)-LTB(2)). Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. 1. Sudhamsu, J. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 19896-901. PMID: 24248355
Reférences	1. Lukashev M, et al. Targeting the lymphotoxin-beta receptor with agonist antibodies as a potential cancer therapy. Cancer Res. 2006 Oct 1;66(19):9617-24. [HW495016]
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade Anti-Human LTBR/TNFR-III Antibody (CBE-11)

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Anti-Human Lymphotoxin beta R/TNFRSF3 Reference Antibody (CBE-11, RUO).pdf

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