Anti-LTBR Polyclonal Antibody (HW495014)

Name: Anti-LTBR Polyclonal Antibody
Brand: abinScience
SKU: HW495014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HW495014

Description

Anti-LTBR Polyclonal Antibody (HW495014) is a rabbit polyclonal antibody detecting LTBR in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human LTBR (Gln31-Met227).

Target

Tumor necrosis factor receptor superfamily member 3, Lymphotoxin-beta receptor, TNFCR, TNF-RIII, Tumor necrosis factor receptor 2-related protein, TNFR3, LTBR, TNFRSF3, Tumor necrosis factor receptor type III, D12S370, TNFR-III, Tumor necrosis factor C receptor

Purification

Purified by antigen affinity column.

Accession

P36941

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Tumor necrosis factor receptor superfamily member 3 (LTBR/TNFR-III) is a ~46 kDa protein. Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Activates NF-kappa-B signaling pathway upon stimulation with lymphotoxin (LTA(1)-LTB(2)). Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.

1. Sudhamsu, J. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 19896-901. PMID: 24248355

Note

For research use only.

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