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Anti-Human beta-NGF Reference Antibody (MEDI-7352, RUO) (HF909086)

Anti-Human beta-NGF Reference Antibody (MEDI-7352, RUO)
Anti-Human beta-NGF Reference Antibody (MEDI-7352, RUO)
Цена(USD):
Спецификация:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Количество:
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  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерHF909086
Реактивность видовHuman
ПримененияELISA, Bioactivity: FCM, Functional assay, Research in vivo
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG
ID клонаMEDI 7352
Цель Beta-NGF, Beta-nerve growth factor, NGF, NGFB
Уровень эндотоксинов < 10 EU/mg
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа P01138
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названияMEDI-7352, MEDI7352, MEDI7352
Фон

Beta-nerve growth factor (NGF/Beta-NGF) is a ~26 kDa protein. Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (Probable). The immature NGF precursor (proNGF) functions as a ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone collapse. In contrast to mature NGF, the precursor form (proNGF) promotes neuronal apoptosis (in vitro). Inhibits metalloproteinase-dependent proteolysis of platelet glycoprotein VI.

1. Einarsdottir, E. et al. (2004) Human molecular genetics 13, 799-805. PMID: 14976160
2. Carvalho, OP. et al. (2011) Journal of medical genetics 48, 131-5. PMID: 20978020
3. Wijeyewickrema, LC. et al. (2010) The Journal of biological chemistry 285, 11793-9. PMID: 20164177
Ссылки 1. Yu H, et al. Osteoarthritis pain[J]. International journal of molecular sciences, 2022, 23(9): 4642. [HF909086]
Примечание For research use only. Not suitable for clinical or therapeutic use.
Изображения
  • Anti-Human beta-NGF Reference Antibody (MEDI-7352, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human NGF/Beta-NGF (MEDI 7352)

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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