Anti-Human OSM/Oncostatin-M Reference Antibody (GSK315234, RUO) (HB745026)

Name: Anti-Human OSM/Oncostatin-M Reference Antibody (GSK315234, RUO)
Brand: abinScience
SKU: HB745026
Price: 176 USD
Availability: InStock

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100ug
1mg
5mg
10mg
25mg
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Vista general

Número de catálogo	HB745026
Descripción	Anti-Human OSM/Oncostatin-M (GSK315234) (HB745026) is a research-grade recombinant antibody targeting Oncostatin-M. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1-kappa
ID de clon	GSK315234
Sistema de expresión	Mammalian cells
Aplicaciones probadas	WB, FCM
Objetivo	Oncostatin-M, OSM
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P13725
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	GSK315234
Fondo	Oncostatin-M (OSM) is a ~28 kDa protein. Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST).
Nota	For research use only. Not suitable for clinical or therapeutic use.

Imágenes

Western blot

Western blot analysis was performed using anti-OSM monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human OSM (Catalog No: HB745011)
Lane 2: negative control
Bioactivity

Detects recombinant human OSM/Oncostatin-M (Catalog No: HB745011) in indirect ELISA
Flow cytometry

Flow-cytometry using anti-human OSM antibody. KG-1 cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an anti-human OSM monoclonal antibody (Catalog HB745026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.