Anti-Human OSM/Oncostatin-M Reference Antibody (GSK 2330811, RUO) (HB745016)

Name: Anti-Human OSM/Oncostatin-M Reference Antibody (GSK 2330811, RUO)
Brand: abinScience
SKU: HB745016
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HB745016
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	GSK 2330811
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Oncostatin-M, OSM
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P13725
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	GSK-2330811, GSK2330811, GSK2330811
Background	Oncostatin-M (OSM) is a ~28 kDa protein. Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST).
References	1. Denton CP, et al. Biological and clinical insights from a randomized phase 2 study of an anti-oncostatin M monoclonal antibody in systemic sclerosis. Rheumatology (Oxford). 2022 Dec 23;62(1):234-242. [HB745016]
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Anti-Human OSM/Oncostatin-M (GSK 2330811)

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Datasheet

Anti-Human OSM/Oncostatin-M Reference Antibody (GSK 2330811, RUO).pdf

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Anti-Human OSM/Oncostatin-M Reference Antibody (GSK 2330811, RUO) (HB745016)

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