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Anti-Influenza A virus HA/Hemagglutinin Reference Antibody (MEDI8852, RUO) (VK515086)

Anti-Influenza A virus HA/Hemagglutinin Reference Antibody (MEDI8852, RUO)
Anti-Influenza A virus HA/Hemagglutinin Reference Antibody (MEDI8852, RUO)
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Vista general
Número de catálogoVK515086
Descripción
Anti-Influenza A virus HA/Hemagglutinin Antibody (MEDI8852) (VK515086) is a research-grade recombinant antibody targeting HA/Hemagglutinin. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especiesInfluenza A virus
AplicacionesELISA, Bioactivity: FCM, Functional assay, Research in vivo
Especie huéspedHuman
ClonalidadMonoclonal
IsotipoIgG1
ID de clonMEDI8852
Objetivo HA, Hemagglutinin, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain
Nivel de endotoxinas < 10 EU/mg
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Forma Liquid
Buffer de almacenamiento 30 mM Histidine, pH5.8, 10% sucrose, 0.02% Tween80

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Hemagglutinin (HA) is a ~62 kDa protein. Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.

Nota For research use only. Not suitable for clinical or therapeutic use.
Imágenes
  • Anti-Influenza A virus HA/Hemagglutinin Reference Antibody (MEDI8852, RUO)

    SDS-PAGE

    SDS-PAGE for Anti-Influenza A virus HA/Hemagglutinin Reference Antibody (MEDI8852, RUO)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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