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Anti-REGN5381 Reference Antibody (REGN9037, RUO) (AB010026)

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Anti-REGN5381 Reference Antibody (REGN9037, RUO)
Anti-REGN5381 Reference Antibody (REGN9037, RUO)
Prix(USD) : --
Spécification :
  • 50ug
  • 100ug
  • 1mg
Nombre :
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  • Reférences

  • Fiche technique

  • SDS

Aperçu
Numéro de catalogueAB010026
Description
Anti-REGN5381 Antibody (REGN9037) (AB010026) is a research-grade recombinant antibody targeting Anti-REGN5381 Antibody. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesGeneral
ApplicationsELISA, Bioactivity: FCM, Functional assay, Research in vivo
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG4
ID de cloneREGN9037
Système d'expression Mammalian cells
Cible Anti-REGN5381 Antibody
Niveau d'endotoxines < 10 EU/mg as determined by LAL method.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:2000-1:20000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Atrial natriuretic peptide receptor 1 (NPR1/NPR-A) is a ~118 kDa protein. Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Plays an essential role in the regulation of endothelial cell senescence and vascular aging. Upon activation by ANP or BNP, stimulates the production of cyclic guanosine monophosphate (cGMP) that promotes vascular tone and volume homeostasis by activation of protein kinase cGMP-dependent 1/PRKG1 and subsequently PRKAA1, thereby controlling blood pressure and maintaining cardiovascular homeostasis.

1. Liu, S. et al. (2025) Nature structural & molecular biology 32, 469-478. PMID: 39543315
2. Long, C. et al. (2022) Aging cell 21, e13699. PMID: 36016499
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-REGN5381 Reference Antibody (REGN9037, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-REGN5381 Antibody (REGN9037)

Reférences
Fiche technique
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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Anti-REGN5381 Reference Antibody (REGN9037, RUO)

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