Anti-REGN5381 Reference Antibody (REGN9037, RUO) (AB010026)

Name: Anti-REGN5381 Reference Antibody (REGN9037, RUO)
Brand: abinScience
SKU: AB010026
Price: 168 USD
Availability: InStock

データシート製品共有情報コピー

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50ug
100ug
1mg

数量:

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

AB010026

説明

Anti-REGN5381 Antibody (REGN9037) (AB010026) is a research-grade recombinant antibody targeting Anti-REGN5381 Antibody. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

種反応性

General

アプリケーション

ELISA, Bioactivity: FCM, Functional assay, Research in vivo

宿主種

Human

クローン性

Monoclonal

アイソタイプ

IgG4

クローンID

REGN9037

発現システム

Mammalian cells

ターゲット

Anti-REGN5381 Antibody

エンドトキシンレベル

< 10 EU/mg as determined by LAL method.

純度

>95% as determined by SDS-PAGE.

精製

Protein A/G purified from cell culture supernatant.

形態

Liquid

保存バッファー

0.01M PBS pH 7.4.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:2000-1:20000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Atrial natriuretic peptide receptor 1 (NPR1/NPR-A) is a ~118 kDa protein. Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Plays an essential role in the regulation of endothelial cell senescence and vascular aging. Upon activation by ANP or BNP, stimulates the production of cyclic guanosine monophosphate (cGMP) that promotes vascular tone and volume homeostasis by activation of protein kinase cGMP-dependent 1/PRKG1 and subsequently PRKAA1, thereby controlling blood pressure and maintaining cardiovascular homeostasis.

1. Liu, S. et al. (2025) Nature structural & molecular biology 32, 469-478. PMID: 39543315

2. Long, C. et al. (2022) Aging cell 21, e13699. PMID: 36016499

注意事項

For research use only. Not suitable for clinical or therapeutic use.

イメージ

SDS-PAGE

SDS-PAGE for Research Grade Anti-REGN5381 Antibody (REGN9037)

参考文献

データシート

Anti-REGN5381 Reference Antibody (REGN9037, RUO).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-REGN5381 Reference Antibody (REGN9037, RUO) (AB010026)

概要

イメージ

参考文献

データシート

SDS