Anti-Human ILDR2 Reference Antibody (Bapotulimab, RUO) (HF648016)

Name: Anti-Human ILDR2 Reference Antibody (Bapotulimab, RUO)
Brand: abinScience
SKU: HF648016
Price: 176 USD
Availability: InStock

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Vista general

Número de catálogo	HF648016
Descripción	Bapotulimab (HF648016) is a research-grade recombinant antibody targeting Immunoglobulin-like domain-containing receptor 2. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG2-Kappa
Sistema de expresión	Mammalian cells
Objetivo	Immunoglobulin-like domain-containing receptor 2, ILDR2, C1orf32
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q71H61
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	BAY-1905254, 2359413-58-2
Fondo	Immunoglobulin-like domain-containing receptor 2 (ILDR2) is a ~71 kDa protein. May be involved in ER stress pathways with effects on lipid homeostasis and insulin secretion. With ILDR1 and LSR, involved in the maintain of the epithelial barrier function through the recruitment of MARVELD2/tricellulin to tricellular tight junctions. Also functions as a B7-like protein family member expressed on immune cells and inflamed tissue and with T-cell inhibitory activity. In the inner ear, may regulate alternative pre-mRNA splicing via binding to TRA2A, TRA2B and SRSF1. 1. Hecht, I. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 200, 2025-2037. PMID: 29431694
Nota	For research use only. Not suitable for clinical or therapeutic use.

Imágenes

Bioactivity

SEC-HPLC detection for Research Grade Bapotulimab.
SDS-PAGE

SDS-PAGE for Research Grade Bapotulimab

Referencias

Datasheet

Anti-Human ILDR2 Reference Antibody (Bapotulimab, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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