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Anti-Human ILDR2 Recombinant Antibody (SAA0176), APC (HF648137)

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Overview
Catalog No.HF648137
Species reactivityHuman
ApplicationsFCM
Host speciesHuman
IsotypeIgG2, kappa
Clone IDSAA0176
ConjugationAPC
Clonality Monoclonal
Target Immunoglobulin-like domain-containing receptor 2, ILDR2, C1orf32
Endotoxin level Please contact with the lab for this information.
Associated products Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10), APC
Accession Q71H61
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Store at 4°C for 12 months. Protect from light. Do not freeze.
Background

Immunoglobulin-like domain-containing receptor 2 (ILDR2) is a ~71 kDa protein. May be involved in ER stress pathways with effects on lipid homeostasis and insulin secretion. With ILDR1 and LSR, involved in the maintain of the epithelial barrier function through the recruitment of MARVELD2/tricellulin to tricellular tight junctions. Also functions as a B7-like protein family member expressed on immune cells and inflamed tissue and with T-cell inhibitory activity. In the inner ear, may regulate alternative pre-mRNA splicing via binding to TRA2A, TRA2B and SRSF1.

1. Hecht, I. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 200, 2025-2037. PMID: 29431694
Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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