Anti-Human ILDR2 Reference Antibody (Bapotulimab, RUO) (HF648016)

Name: Anti-Human ILDR2 Reference Antibody (Bapotulimab, RUO)
Brand: abinScience
SKU: HF648016
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HF648016
Description	Bapotulimab (HF648016) is a research-grade recombinant antibody targeting Immunoglobulin-like domain-containing receptor 2. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG2-Kappa
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Immunoglobulin-like domain-containing receptor 2, ILDR2, C1orf32
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q71H61
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	BAY-1905254, 2359413-58-2
Background	Immunoglobulin-like domain-containing receptor 2 (ILDR2) is a ~71 kDa protein. May be involved in ER stress pathways with effects on lipid homeostasis and insulin secretion. With ILDR1 and LSR, involved in the maintain of the epithelial barrier function through the recruitment of MARVELD2/tricellulin to tricellular tight junctions. Also functions as a B7-like protein family member expressed on immune cells and inflamed tissue and with T-cell inhibitory activity. In the inner ear, may regulate alternative pre-mRNA splicing via binding to TRA2A, TRA2B and SRSF1. 1. Hecht, I. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 200, 2025-2037. PMID: 29431694
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

SEC-HPLC detection for Research Grade Bapotulimab.
SDS-PAGE

SDS-PAGE for Research Grade Bapotulimab

References

Datasheet

Anti-Human ILDR2 Reference Antibody (Bapotulimab, RUO).pdf

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Anti-Human ILDR2 Reference Antibody (Bapotulimab, RUO) (HF648016)

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Datasheet

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