Anti-Human ILDR2 Reference Antibody (Bapotulimab, RUO) (HF648016)

Name: Anti-Human ILDR2 Reference Antibody (Bapotulimab, RUO)
Brand: abinScience
SKU: HF648016
Price: 176 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HF648016
Description	Bapotulimab (HF648016) is a research-grade recombinant antibody targeting Immunoglobulin-like domain-containing receptor 2. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG2-Kappa
Système d'expression	Mammalian cells
Cible	Immunoglobulin-like domain-containing receptor 2, ILDR2, C1orf32
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q71H61
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	BAY-1905254, 2359413-58-2
Contexte	Immunoglobulin-like domain-containing receptor 2 (ILDR2) is a ~71 kDa protein. May be involved in ER stress pathways with effects on lipid homeostasis and insulin secretion. With ILDR1 and LSR, involved in the maintain of the epithelial barrier function through the recruitment of MARVELD2/tricellulin to tricellular tight junctions. Also functions as a B7-like protein family member expressed on immune cells and inflamed tissue and with T-cell inhibitory activity. In the inner ear, may regulate alternative pre-mRNA splicing via binding to TRA2A, TRA2B and SRSF1. 1. Hecht, I. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 200, 2025-2037. PMID: 29431694
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

SEC-HPLC detection for Research Grade Bapotulimab.
SDS-PAGE

SDS-PAGE for Research Grade Bapotulimab

Reférences

Fiche technique

Anti-Human ILDR2 Reference Antibody (Bapotulimab, RUO).pdf

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