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Anti-Human ILDR2 Reference Antibody (Bapotulimab, RUO) (HF648016)

Anti-Human ILDR2 Reference Antibody (Bapotulimab, RUO)
Anti-Human ILDR2 Reference Antibody (Bapotulimab, RUO)
Anti-Human ILDR2 Reference Antibody (Bapotulimab, RUO)
Anti-Human ILDR2 Reference Antibody (Bapotulimab, RUO)
Цена(USD):
Спецификация:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Количество:
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  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерHF648016
Описание
Bapotulimab (HF648016) is a research-grade recombinant antibody targeting Immunoglobulin-like domain-containing receptor 2. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видовHuman
ПримененияELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG2-Kappa
Система экспрессии Mammalian cells
Цель Immunoglobulin-like domain-containing receptor 2, ILDR2, C1orf32
Уровень эндотоксинов < 10 EU/mg
Чистота >95% purity as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа Q71H61
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названияBAY-1905254, 2359413-58-2
Фон

Immunoglobulin-like domain-containing receptor 2 (ILDR2) is a ~71 kDa protein. May be involved in ER stress pathways with effects on lipid homeostasis and insulin secretion. With ILDR1 and LSR, involved in the maintain of the epithelial barrier function through the recruitment of MARVELD2/tricellulin to tricellular tight junctions. Also functions as a B7-like protein family member expressed on immune cells and inflamed tissue and with T-cell inhibitory activity. In the inner ear, may regulate alternative pre-mRNA splicing via binding to TRA2A, TRA2B and SRSF1.

1. Hecht, I. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 200, 2025-2037. PMID: 29431694
Примечание For research use only. Not suitable for clinical or therapeutic use.
Изображения
  • Anti-Human ILDR2 Reference Antibody (Bapotulimab, RUO)

    Bioactivity

    SEC-HPLC detection for Research Grade Bapotulimab.

  • Anti-Human ILDR2 Reference Antibody (Bapotulimab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Bapotulimab

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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