



| Каталожный номер | HF648016 |
|---|---|
| Описание |
Bapotulimab (HF648016) is a research-grade recombinant antibody targeting Immunoglobulin-like domain-containing receptor 2. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| Реактивность видов | Human |
| Применения | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Хозяинский вид | Human |
| Клоональность | Monoclonal |
| Изотип | IgG2-Kappa |
| Система экспрессии | Mammalian cells |
| Цель | Immunoglobulin-like domain-containing receptor 2, ILDR2, C1orf32 |
| Уровень эндотоксинов | < 10 EU/mg |
| Чистота | >95% purity as determined by SDS-PAGE. |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | Q71H61 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | BAY-1905254, 2359413-58-2 |
| Фон | Immunoglobulin-like domain-containing receptor 2 (ILDR2) is a ~71 kDa protein. May be involved in ER stress pathways with effects on lipid homeostasis and insulin secretion. With ILDR1 and LSR, involved in the maintain of the epithelial barrier function through the recruitment of MARVELD2/tricellulin to tricellular tight junctions. Also functions as a B7-like protein family member expressed on immune cells and inflamed tissue and with T-cell inhibitory activity. In the inner ear, may regulate alternative pre-mRNA splicing via binding to TRA2A, TRA2B and SRSF1. 1. Hecht, I. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 200, 2025-2037. PMID: 29431694 |
| Примечание | For research use only. Not suitable for clinical or therapeutic use. |

SEC-HPLC detection for Research Grade Bapotulimab.

SDS-PAGE for Research Grade Bapotulimab




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