Anti-Human CCL11/Eotaxin Reference Antibody (Bertilimumab, RUO) (HW762016)

Name: Anti-Human CCL11/Eotaxin Reference Antibody (Bertilimumab, RUO)
Brand: abinScience
SKU: HW762016
Price: 176 USD
Availability: InStock

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Numéro de catalogue	HW762016
Description	Research Grade Bertilimumab (HW762016) is a human monoclonal antibody detecting Small-inducible cytokine A11 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG4-kappa
Système d'expression	Mammalian cells
Espèces	Human
Cible	Small-inducible cytokine A11, SCYA11, Eotaxin, CCL11, Eosinophil chemotactic protein, C-C motif chemokine 11
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P51671
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	CAT-213, iCo-008, 375348-49-5
Contexte	Eotaxin (Small-inducible cytokine A11,SCYA11,Eotaxin,CCL11,Eosinophil chemotactic protein,C-C motif chemokine 11) is a ~10 kDa protein. Chemokine that plays a central role in both allergic and non-allergic inflammatory reactions by inducing the migration of different leukocyte types including eosinophils, basophils, macrophages and dendritic cells. Exerts its effects primarily by binding to the CCR3 receptor. Induces also chemotaxis of endothelial cells and promotes angiogenesis by activating the PI3K/Akt pathway. 1. Garcia-Zepeda, EA. et al. (1996) Nature medicine 2, 449-56. PMID: 8597956 2. Wakabayashi, K. et al. (2021) Scientific reports 11, 7937. PMID: 33846499 3. Kitaura, M. et al. (1996) The Journal of biological chemistry 271, 7725-30. PMID: 8631813 4. Park, JY. et al. (2017) Journal of receptor and signal transduction research 37, 416-421. PMID: 28279120
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207) Human IgG4 (S228P & L235E) Recombinant Isotype Control Antibody (HyHEL-10) (HP614107) Human IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107)

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SDS-PAGE for Research Grade Bertilimumab

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Anti-Human CCL11/Eotaxin Reference Antibody (Bertilimumab, RUO).pdf

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