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Anti-Human CCL11/Eotaxin Recombinant Antibody (SAA0458) (HW762107)

Anti-Human CCL11/Eotaxin Recombinant Antibody (SAA0458)
Anti-Human CCL11/Eotaxin Recombinant Antibody (SAA0458)
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Overview
Catalog No.HW762107
Species reactivityHuman
ApplicationsELISA, FCM
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDSAA0458
Clonality Monoclonal
Target Small-inducible cytokine A11, SCYA11, Eotaxin, CCL11, Eosinophil chemotactic protein, C-C motif chemokine 11, Eotaxin1, Eotaxin-1
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P51671
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 0.09% Sodium azide.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Eotaxin (CCL11) is a ~10 kDa protein. Chemokine that plays a central role in both allergic and non-allergic inflammatory reactions by inducing the migration of different leukocyte types including eosinophils, basophils, macrophages and dendritic cells. Exerts its effects primarily by binding to the CCR3 receptor. Induces also chemotaxis of endothelial cells and promotes angiogenesis by activating the PI3K/Akt pathway.

1. Garcia-Zepeda, EA. et al. (1996) Nature medicine 2, 449-56. PMID: 8597956
2. Wakabayashi, K. et al. (2021) Scientific reports 11, 7937. PMID: 33846499
3. Kitaura, M. et al. (1996) The Journal of biological chemistry 271, 7725-30. PMID: 8631813
4. Park, JY. et al. (2017) Journal of receptor and signal transduction research 37, 416-421. PMID: 28279120
Note For research use only.
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  • Anti-Human CCL11/Eotaxin Recombinant Antibody (SAA0458)

    SDS-PAGE

    SDS-PAGE for Anti-Human CCL11/Eotaxin Antibody (SAA0458)

References
Formula
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