Anti-Human CCL11/Eotaxin Reference Antibody (Bertilimumab, RUO) (HW762016)

Name: Anti-Human CCL11/Eotaxin Reference Antibody (Bertilimumab, RUO)
Brand: abinScience
SKU: HW762016
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HW762016
Description	Research Grade Bertilimumab (HW762016) is a human monoclonal antibody detecting Small-inducible cytokine A11 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG4-kappa
Expression system	Mammalian cells
Species	Human
Clonality	Monoclonal
Target	Small-inducible cytokine A11, SCYA11, Eotaxin, CCL11, Eosinophil chemotactic protein, C-C motif chemokine 11
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P51671
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CAT-213, iCo-008, 375348-49-5
Background	Eotaxin (Small-inducible cytokine A11,SCYA11,Eotaxin,CCL11,Eosinophil chemotactic protein,C-C motif chemokine 11) is a ~10 kDa protein. Chemokine that plays a central role in both allergic and non-allergic inflammatory reactions by inducing the migration of different leukocyte types including eosinophils, basophils, macrophages and dendritic cells. Exerts its effects primarily by binding to the CCR3 receptor. Induces also chemotaxis of endothelial cells and promotes angiogenesis by activating the PI3K/Akt pathway. 1. Garcia-Zepeda, EA. et al. (1996) Nature medicine 2, 449-56. PMID: 8597956 2. Wakabayashi, K. et al. (2021) Scientific reports 11, 7937. PMID: 33846499 3. Kitaura, M. et al. (1996) The Journal of biological chemistry 271, 7725-30. PMID: 8631813 4. Park, JY. et al. (2017) Journal of receptor and signal transduction research 37, 416-421. PMID: 28279120
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade Bertilimumab

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Datasheet

Anti-Human CCL11/Eotaxin Reference Antibody (Bertilimumab, RUO).pdf

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Anti-Human CCL11/Eotaxin Reference Antibody (Bertilimumab, RUO) (HW762016)

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