Anti-Human CCL11/Eotaxin Reference Antibody (Bertilimumab, RUO) (HW762016)

Name: Anti-Human CCL11/Eotaxin Reference Antibody (Bertilimumab, RUO)
Brand: abinScience
SKU: HW762016
Price: 176 USD
Availability: InStock

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Обзор

Каталожный номер	HW762016
Описание	Research Grade Bertilimumab (HW762016) is a human monoclonal antibody detecting Small-inducible cytokine A11 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications.
Реактивность видов	Human
Применения	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG4-kappa
Система экспрессии	Mammalian cells
Виды	Human
Цель	Small-inducible cytokine A11, SCYA11, Eotaxin, CCL11, Eosinophil chemotactic protein, C-C motif chemokine 11
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P51671
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	CAT-213, iCo-008, 375348-49-5
Фон	Eotaxin (Small-inducible cytokine A11,SCYA11,Eotaxin,CCL11,Eosinophil chemotactic protein,C-C motif chemokine 11) is a ~10 kDa protein. Chemokine that plays a central role in both allergic and non-allergic inflammatory reactions by inducing the migration of different leukocyte types including eosinophils, basophils, macrophages and dendritic cells. Exerts its effects primarily by binding to the CCR3 receptor. Induces also chemotaxis of endothelial cells and promotes angiogenesis by activating the PI3K/Akt pathway. 1. Garcia-Zepeda, EA. et al. (1996) Nature medicine 2, 449-56. PMID: 8597956 2. Wakabayashi, K. et al. (2021) Scientific reports 11, 7937. PMID: 33846499 3. Kitaura, M. et al. (1996) The Journal of biological chemistry 271, 7725-30. PMID: 8631813 4. Park, JY. et al. (2017) Journal of receptor and signal transduction research 37, 416-421. PMID: 28279120
Примечание	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207) Human IgG4 (S228P & L235E) Recombinant Isotype Control Antibody (HyHEL-10) (HP614107) Human IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107)

Изображения

SDS-PAGE

SDS-PAGE for Research Grade Bertilimumab

Ссылки

Даташит

Anti-Human CCL11/Eotaxin Reference Antibody (Bertilimumab, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

C₁ × V₁ = C₂ × V₂

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C₁ (Stock Conc.)

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