Research Grade Bevifimod (JN856016)

Name: Research Grade Bevifimod
Brand: abinScience
SKU: JN856016
Price: 370 USD
Availability: InStock

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Numéro de catalogue	JN856016
Description	Research Grade Bevifimod (JN856016) is a rabbit polyclonal antibody detecting Immunoglobulin G-binding protein A in Functional assay.
Applications	Functional assay
Clonalité	Monoclonal
Système d'expression	Mammalian cells
Nature	Recombinant
Cible	Immunoglobulin G-binding protein A, IgG-binding protein A, Staphylococcal protein A, SpA, spa
Niveau d'endotoxines	< 10 EU/mg as determined by LAL method.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P38507
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte	Immunoglobulin G-binding protein A is a ~55 kDa protein. Plays a role in the inhibition of the host innate and adaptive immune responses. Possesses five immunoglobulin-binding domains that capture both the fragment crystallizable region (Fc region) and the Fab region (part of Ig that identifies antigen) of immunoglobulins. In turn, Staphylococcus aureus is protected from phagocytic killing via inhibition of Ig Fc region. In addition, the host elicited B-cell response is prevented due to a decrease of antibody-secreting cell proliferation that enter the bone marrow, thereby decreasing long-term antibody production. Inhibits osteogenesis by preventing osteoblast proliferation and expression of alkaline phosphatase, type I collagen, osteopontin and osteocalcin.
Note	For research use only. Not suitable for clinical or therapeutic use.

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Research Grade Bevifimod.pdf

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Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Research Grade Bevifimod (JN856016)

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