Anti-Human CD131/CSF2RB Reference Antibody (Birinkibart, RUO) (HW498036)

Name: Anti-Human CD131/CSF2RB Reference Antibody (Birinkibart, RUO)
Brand: abinScience
SKU: HW498036
Price: 176 USD
Availability: InStock

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100ug
1mg
5mg
10mg
25mg
50mg
100mg

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Número de catálogo	HW498036
Descripción	birinkibart (HW498036) is a research-grade recombinant antibody targeting CD131. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG4, Kappa
Especies	Human
Objetivo	CD131/CSF2RB
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% as determined by SDS-PAGE.
Número de acceso	P32927
Forma	Liquid
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	2894136-82-2
Fondo	Cytokine receptor common subunit beta (CD131/CSF2RB) is a ~97 kDa protein. Cell surface receptor that plays a role in immune response and controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Acts by forming an heterodimeric receptor through interaction with different partners such as IL3RA, IL5RA or CSF2RA. In turn, participates in various signaling pathways including interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor/CSF2 pathways. In unstimulated conditions, interacts constitutively with JAK1 and ligand binding leads to JAK1 stimulation and subsequent activation of the JAK-STAT pathway. 1. Tavernier, J. et al. (1992) Proceedings of the National Academy of Sciences of the United States of America 89, 7041-5. PMID: 1495999 2. Ogata, N. et al. (1998) Blood 91, 2264-71. PMID: 9516124
Nota	For research use only. Not suitable for clinical or therapeutic use.