Anti-Human CD8 alpha Reference Antibody (Crefmirlimab, RUO) (HP158016)

Name: Anti-Human CD8 alpha Reference Antibody (Crefmirlimab, RUO)
Brand: abinScience
SKU: HP158016
Price: 176 USD
Availability: InStock

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100ug
1mg
5mg
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50mg
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Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo	HP158016
Descripción	Crefmirlimab (HP158016) is a research-grade recombinant antibody targeting CD8. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	(scFv-kappa-heavy) -h- CH3
Sistema de expresión	Mammalian cells
Objetivo	T-cell surface glycoprotein CD8 alpha chain, CD8a, T-lymphocyte differentiation antigen T8/Leu-2, MAL, CD8A
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Purified by ion exchange chromatography.
Número de acceso	P01732
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	89Zr-IAB22M2C, IAB22M2C, 89Zr-Df-IAB22M2C, 2611099-93-3
Fondo	T-cell surface glycoprotein CD8 alpha chain (CD8A) is a ~25 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.
Nota	For research use only. Not suitable for clinical or therapeutic use.

Imágenes

Bioactivity

Detects CD8A in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Crefmirlimab.

Referencias

Datasheet

Anti-Human CD8 alpha Reference Antibody (Crefmirlimab, RUO).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

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