中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HP158016 |
|---|---|
| 説明 |
Crefmirlimab (HP158016) is a research-grade recombinant antibody targeting CD8. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 種反応性 | Human |
| アプリケーション | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | (scFv-kappa-heavy) -h- CH3 |
| 発現システム | Mammalian cells |
| ターゲット | T-cell surface glycoprotein CD8 alpha chain, CD8a, T-lymphocyte differentiation antigen T8/Leu-2, MAL, CD8A |
| エンドトキシンレベル | < 10 EU/mg |
| 純度 | >95% purity as determined by SDS-PAGE. |
| 精製 | Purified by ion exchange chromatography. |
| アクセッション番号 | P01732 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | 89Zr-IAB22M2C, IAB22M2C, 89Zr-Df-IAB22M2C, 2611099-93-3 |
| 背景 | T-cell surface glycoprotein CD8 alpha chain (CD8A) is a ~25 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
Detects CD8A in indirect ELISAs.
SDS-PAGE for Research Grade Crefmirlimab.
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
