Research Grade Efgivanermin Alfa (HV475036)

Name: Research Grade Efgivanermin Alfa
Brand: abinScience
SKU: HV475036
Price: 424 USD
Availability: InStock

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概要
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データシート
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概要

カタログ番号	HV475036
説明	Efgivanermin Alfa (HV475036) is a research-grade recombinant antibody targeting CD357. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Functional assay, Research in vivo
アイソタイプ	Fusion - [IGHG1 Fc (Fragment constant) - [CORO1A (coronin 1A, actin-binding protein) - TNFSF18 (TNF superfamily member 18, AITRL, TL6, GITRL)]2]3 (hexamer)
発現システム	Mammalian cells
ターゲット	Activation-inducible TNFR family receptor, GITR, TNFRSF18, CD357, Tumor necrosis factor receptor superfamily member 18, AITR, Glucocorticoid-induced TNFR-related protein
エンドトキシンレベル	< 10 EU/mg
純度	>95% purity as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	Q9Y5U5
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	MEDI-1873, MEDI1873, 1807864-13-6
背景	Tumor necrosis factor receptor superfamily member 18 (CD357/GITR) is a ~26 kDa protein. Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
注意事項	For research use only. Not suitable for clinical or therapeutic use.