

| Número de catálogo | HF703016 |
|---|---|
| Descripción |
Efparepoetin Alfa (HF703016) is a research-grade recombinant antibody targeting EPO. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| Reactividad de especies | Human |
| Aplicaciones | ELISA, Functional assay, Research in vivo |
| Clonalidad | Monoclonal |
| Isotipo | Human erythropoietin fragment fused via peptide linker to a Fc fragment of immunoglobulin G2 |
| Sistema de expresión | Mammalian cells |
| Naturaleza | Recombinant |
| Objetivo | EPO, Erythropoietin, Epoetin |
| Nivel de endotoxinas | < 10 EU/mg as determined by LAL method. |
| Pureza | >95% as determined by SDS-PAGE. |
| Purificación | Protein A/G purified from cell culture supernatant. |
| Número de acceso | P01588 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Nombres alternativos | 2761347-19-5 |
| Fondo | Erythropoietin (EPO) is a ~21 kDa protein. Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. 1. Kim, AR. et al. (2017) Cell 168, 1053-1064.e15. PMID: 28283061 2. Syed, RS. et al. (1998) Nature 395, 511-6. PMID: 9774108 |
| Nota | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Efparepoetin Alfa




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