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Research Grade Efparepoetin Alfa (HF703016)

Research Grade Efparepoetin Alfa
Research Grade Efparepoetin Alfa
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Aperçu
Numéro de catalogueHF703016
Description
Efparepoetin Alfa (HF703016) is a research-grade recombinant antibody targeting EPO. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesHuman
ApplicationsELISA, Functional assay, Research in vivo
ClonalitéMonoclonal
IsotypeHuman erythropoietin fragment fused via peptide linker to a Fc fragment of immunoglobulin G2
Système d'expression Mammalian cells
Nature Recombinant
Cible EPO, Erythropoietin, Epoetin
Niveau d'endotoxines < 10 EU/mg as determined by LAL method.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P01588
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs2761347-19-5
Contexte

Erythropoietin (EPO) is a ~21 kDa protein. Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.

1. Kim, AR. et al. (2017) Cell 168, 1053-1064.e15. PMID: 28283061
2. Syed, RS. et al. (1998) Nature 395, 511-6. PMID: 9774108
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Research Grade Efparepoetin Alfa

    SDS-PAGE

    SDS-PAGE for Research Grade Efparepoetin Alfa

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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