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| カタログ番号 | HF703016 |
|---|---|
| 説明 |
Efparepoetin Alfa (HF703016) is a research-grade recombinant antibody targeting EPO. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 種反応性 | Human |
| アプリケーション | ELISA, Functional assay, Research in vivo |
| クローン性 | Monoclonal |
| アイソタイプ | Human erythropoietin fragment fused via peptide linker to a Fc fragment of immunoglobulin G2 |
| 発現システム | Mammalian cells |
| 性質 | Recombinant |
| ターゲット | EPO, Erythropoietin, Epoetin |
| エンドトキシンレベル | < 10 EU/mg as determined by LAL method. |
| 純度 | >95% as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | P01588 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | 2761347-19-5 |
| 背景 | Erythropoietin (EPO) is a ~21 kDa protein. Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. 1. Kim, AR. et al. (2017) Cell 168, 1053-1064.e15. PMID: 28283061 2. Syed, RS. et al. (1998) Nature 395, 511-6. PMID: 9774108 |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Efparepoetin Alfa
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