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Research Grade Efprezimod alfa (HB630036)

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Research Grade Efprezimod alfa
Research Grade Efprezimod alfa
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Vista general
Número de catálogoHB630036
Descripción
Research Grade Efprezimod alfa (HB630036) is a human monoclonal antibody detecting Signal transducer CD24 in FuncS. Suitable for Human.
Reactividad de especiesHuman
AplicacionesFuncS
Especie huéspedHuman
ClonalidadMonoclonal
IsotipoFusion - [CD24 (CD24 molecule, CD24 antigen (small cell lung carcinoma cluster 4 antigen))]2 - IGHG1 Fc
Sistema de expresión Mammalian cells
Naturaleza Recombinant
Objetivo Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen, CD24, CD24, CD24A
Nivel de endotoxinas < 10 EU/mg as determined by LAL method.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P25063
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Signal transducer CD24 (Siglec-10) is a ~8 kDa protein. May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90.

1. Suzuki, T. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 166, 5567-77. PMID: 11313396
Nota For research use only. Not suitable for clinical or therapeutic use.
Isotype Control VHH-hFc (IgG1) Isotype Control antibody (cAb-Lys2) (ZP167307)
Imágenes
  • Research Grade Efprezimod alfa

    SDS-PAGE

    SDS-PAGE for Research Grade Efprezimod alfa

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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