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Research Grade Efprezimod alfa (HB630036)

Research Grade Efprezimod alfa
Research Grade Efprezimod alfa
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Aperçu
Numéro de catalogueHB630036
Description
Research Grade Efprezimod alfa (HB630036) is a human monoclonal antibody detecting Signal transducer CD24 in FuncS. Suitable for Human.
Reactivité des espècesHuman
ApplicationsFuncS
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeFusion - [CD24 (CD24 molecule, CD24 antigen (small cell lung carcinoma cluster 4 antigen))]2 - IGHG1 Fc
Système d'expression Mammalian cells
Nature Recombinant
Cible Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen, CD24, CD24, CD24A
Niveau d'endotoxines < 10 EU/mg as determined by LAL method.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P25063
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Signal transducer CD24 (Siglec-10) is a ~8 kDa protein. May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90.

1. Suzuki, T. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 166, 5567-77. PMID: 11313396
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype Control VHH-hFc (IgG1) Isotype Control antibody (cAb-Lys2) (ZP167307)
Images
  • Research Grade Efprezimod alfa

    SDS-PAGE

    SDS-PAGE for Research Grade Efprezimod alfa

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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