Anti-Human IL-9 Reference Antibody (Enokizumab, RUO) (HB771016)

Name: Anti-Human IL-9 Reference Antibody (Enokizumab, RUO)
Brand: abinScience
SKU: HB771016
Price: 176 USD
Availability: InStock

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Vista general

Número de catálogo	HB771016
Descripción	Research Grade Enokizumab (HB771016) is a humanized monoclonal antibody detecting T-cell growth factor P40 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1-kappa
Sistema de expresión	Mammalian cells
Especies	Human
Objetivo	T-cell growth factor P40, Cytokine P40, IL9, Interleukin-9, IL-9
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P15248
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	7F3com-2H2, MEDI-528, 909875-08-7
Fondo	Interleukin-9 (T-cell growth factor P40,Cytokine P40,IL9,Interleukin-9,IL-9) is a ~15 kDa protein. Multifunctional cytokine secreted mainly by T-helper 2 lymphocytes and also mast cells or NKT cells that plays important roles in the immune response against parasites. Affects intestinal epithelial permeability and adaptive immunity. In addition, induces the differentiation of specific T-cell subsets such as IL-17 producing helper T-cells (TH17) and also proliferation and differentiation of mast cells. Mechanistically, exerts its biological effects through a receptor composed of IL9R subunit and a signal transducing subunit IL2RG. Receptor stimulation results in the rapid activation of JAK1 and JAK3 kinase activities leading to STAT1, STAT3 and STAT5-mediated transcriptional programs. 1. Renga, G. et al. (2018) Cell reports 23, 1767-1778. PMID: 29742432
Nota	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Imágenes

Bioactivity

SEC-HPLC detection for Research Grade Enokizumab.
SDS-PAGE

SDS-PAGE for Research Grade Enokizumab.

Referencias

Datasheet

Anti-Human IL-9 Reference Antibody (Enokizumab, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Mass

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

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Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

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