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Anti-Human IL-9 Recombinant Antibody (SAA0377) (HB771107)

Anti-Human IL-9 Recombinant Antibody (SAA0377)
Anti-Human IL-9 Recombinant Antibody (SAA0377)
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Overview
Catalog No.HB771107
Species reactivityHuman
ApplicationsBlocking, ELISA, FCM
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDSAA0377
Clonality Monoclonal
Target T-cell growth factor P40, Cytokine P40, IL9, Interleukin-9, IL-9
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P15248
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 0.09% Sodium azide.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Interleukin-9 (IL9) is a ~15 kDa protein. Multifunctional cytokine secreted mainly by T-helper 2 lymphocytes and also mast cells or NKT cells that plays important roles in the immune response against parasites. Affects intestinal epithelial permeability and adaptive immunity. In addition, induces the differentiation of specific T-cell subsets such as IL-17 producing helper T-cells (TH17) and also proliferation and differentiation of mast cells. Mechanistically, exerts its biological effects through a receptor composed of IL9R subunit and a signal transducing subunit IL2RG. Receptor stimulation results in the rapid activation of JAK1 and JAK3 kinase activities leading to STAT1, STAT3 and STAT5-mediated transcriptional programs.

1. Renga, G. et al. (2018) Cell reports 23, 1767-1778. PMID: 29742432
Note For research use only.
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  • Anti-Human IL-9 Recombinant Antibody (SAA0377)

    SDS-PAGE

    SDS-PAGE for Anti-Human IL9 Antibody (SAA0377)

References
Formula
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