Anti-Human IL-9 Reference Antibody (Enokizumab, RUO) (HB771016)

Name: Anti-Human IL-9 Reference Antibody (Enokizumab, RUO)
Brand: abinScience
SKU: HB771016
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HB771016
Description	Research Grade Enokizumab (HB771016) is a humanized monoclonal antibody detecting T-cell growth factor P40 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1-kappa
Expression system	Mammalian cells
Species	Human
Clonality	Monoclonal
Target	T-cell growth factor P40, Cytokine P40, IL9, Interleukin-9, IL-9
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P15248
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	7F3com-2H2, MEDI-528, 909875-08-7
Background	Interleukin-9 (T-cell growth factor P40,Cytokine P40,IL9,Interleukin-9,IL-9) is a ~15 kDa protein. Multifunctional cytokine secreted mainly by T-helper 2 lymphocytes and also mast cells or NKT cells that plays important roles in the immune response against parasites. Affects intestinal epithelial permeability and adaptive immunity. In addition, induces the differentiation of specific T-cell subsets such as IL-17 producing helper T-cells (TH17) and also proliferation and differentiation of mast cells. Mechanistically, exerts its biological effects through a receptor composed of IL9R subunit and a signal transducing subunit IL2RG. Receptor stimulation results in the rapid activation of JAK1 and JAK3 kinase activities leading to STAT1, STAT3 and STAT5-mediated transcriptional programs. 1. Renga, G. et al. (2018) Cell reports 23, 1767-1778. PMID: 29742432
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

SEC-HPLC detection for Research Grade Enokizumab.
SDS-PAGE

SDS-PAGE for Research Grade Enokizumab.

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Datasheet

Anti-Human IL-9 Reference Antibody (Enokizumab, RUO).pdf

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Anti-Human IL-9 Reference Antibody (Enokizumab, RUO) (HB771016)

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