Anti-Human IL-9 Reference Antibody (Enokizumab, RUO) (HB771016)

Name: Anti-Human IL-9 Reference Antibody (Enokizumab, RUO)
Brand: abinScience
SKU: HB771016
Price: 176 USD
Availability: InStock

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Спецификация:

100ug
1mg
5mg
10mg
25mg
50mg
100mg

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Обзор
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Обзор

Каталожный номер	HB771016
Описание	Research Grade Enokizumab (HB771016) is a humanized monoclonal antibody detecting T-cell growth factor P40 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications.
Реактивность видов	Human
Применения	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG1-kappa
Система экспрессии	Mammalian cells
Виды	Human
Цель	T-cell growth factor P40, Cytokine P40, IL9, Interleukin-9, IL-9
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P15248
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	7F3com-2H2, MEDI-528, 909875-08-7
Фон	Interleukin-9 (T-cell growth factor P40,Cytokine P40,IL9,Interleukin-9,IL-9) is a ~15 kDa protein. Multifunctional cytokine secreted mainly by T-helper 2 lymphocytes and also mast cells or NKT cells that plays important roles in the immune response against parasites. Affects intestinal epithelial permeability and adaptive immunity. In addition, induces the differentiation of specific T-cell subsets such as IL-17 producing helper T-cells (TH17) and also proliferation and differentiation of mast cells. Mechanistically, exerts its biological effects through a receptor composed of IL9R subunit and a signal transducing subunit IL2RG. Receptor stimulation results in the rapid activation of JAK1 and JAK3 kinase activities leading to STAT1, STAT3 and STAT5-mediated transcriptional programs. 1. Renga, G. et al. (2018) Cell reports 23, 1767-1778. PMID: 29742432
Примечание	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Изображения

Bioactivity

SEC-HPLC detection for Research Grade Enokizumab.
SDS-PAGE

SDS-PAGE for Research Grade Enokizumab.

Ссылки

Даташит

Anti-Human IL-9 Reference Antibody (Enokizumab, RUO).pdf

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Formula

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Working Solution

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