Anti-Human B7-H4 Reference Antibody (Felmetatug, RUO) (HV721116)

Name: Anti-Human B7-H4 Reference Antibody (Felmetatug, RUO)
Brand: abinScience
SKU: HV721116
Price: 176 USD
Availability: InStock

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Numéro de catalogue	HV721116
Description	felmetatug (HV721116) is a research-grade recombinant antibody targeting VTCN1/B7-H4. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1, Kappa
Espèces	Human
Cible	VTCN1/B7-H4
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% as determined by SDS-PAGE.
Numéro d'accès	Q7Z7D3
Forme	Liquid
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	2924808-29-5
Contexte	V-set domain-containing T-cell activation inhibitor 1 (VTCN1/B7-H4) is a ~30 kDa protein. Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.
Note	For research use only. Not suitable for clinical or therapeutic use.